Kobayashi-Kirschvink Lab @ UChicago

Publication

  • Koseki J. Kobayashi-Kirschvink, Jeon Woong Kang, Peter T.C. So, “High-speed Raman microscopy by total internal reflection,” manuscript under preparation, patent filed
  • Leonardo Bianchi, Arianna Bresci, Koseki J. Kobayashi-Kirschvink, Gabriela Paroni, Paola Saccomandi, Peter T. C. So, Jeon Woong Kang, “A Multimodal Imaging Framework to Advance Phenotyping of Living Label-free Breast Cancer Cells,” Journal of Visualized Experiments, accepted
  • Ken-ichiro F Kamei, Koseki J Kobayashi-Kirschvink, Takashi Nozoe, Hidenori Nakaoka, Miki Umetani, Yuichi Wakamoto. “Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns,” eLife 14:RP101485, 2025
  • Bruno, Giulia, Michal Lipinski, J. Kobayashi-Kirschvink, Christian Tentellino, Peter T. C. So, Jeon Woong Kang, and Francesco De Angelis. 2025. “Label-Free Detection of Biochemical Changes during Cortical Organoid Maturation via Raman Spectroscopy and Machine Learning.” Analytical Chemistry 97 (9): 5029–37.
  • Arianna Bresci, Koseki J. Kobayashi-Kirschvink, Giulio N. F. Cerullo, Renzo Vanna, Peter T. C. So, Dario Polli, Jeon W. Kang, “Superior Label-free Morpho-Molecular Phenotyping of Living Cancer Cells by Combined Raman Spectroscopy and Phase Tomography,” Communications Biology, 7, 785 (2024)
  • Koseki J. Kobayashi-Kirschvink, Peter T. C. So, Jeon Woong Kang, “High-throughput Raman spectroscopy by horizontally shifted collection fibers,” Analytical Chemistry, 2024, 96, 31, 12598–12601 (cover highlight) link 
  • Pu-Ting Dong, Jing Tian, Koseki J. Kobayashi-Kirschvink, Lujia Cen, Jeffrey S. McLean, Batbileg Bor, Wenyuan Shi, Xuesong He, “Ultrasmall epibiont induces lipid droplet production inside its host bacteria,” The ISME Journal, Volume 18, Issue 1, January 2024.
  • Johain R. Ounadjela*, Ke Zhang*, Koseki J. Kobayashi-Kirschvink*, Kang Jin*, Andrew Russell*, Andreas I. Lackner*, Claire Callahan, Francesca Viggiani, Kushal K. Dey, Karthik Jagadeesh, Theresa Maxian, Anna-Maria Prandstetter,  Naeem Nadaf, Qiyu Gong, Ruth Raichur, Morgan L. Zvezdov, Mingyang Hui, Mattew Simpson, Xinwen Liu, Wei Min, Martin Knöfler, Fei Chen, Sandra Haider, Jian Shu, “Spatial multiomic landscape of the human placenta at molecular resolution ,” Nature Medicine, 10.1038/s41591-024-03073-9, link. *equal contributions
  • Silvia Ghislanzoni, Jeon Woong Kang, Arianna Bresci, Andrea Masella, Matteo Bregonzio, Koseki J. Kobayashi-Kirschvink, Dario Polli, Italia Bongarzone, Peter T. C. So, “Optical Diffraction Tomography and Raman Confocal Microscopy for the Investigation of Vacuoles Associated with Cancer Senescent Engulfing Cells,Biosensors 2023, 13(11), 973
  • Koseki J. Kobayashi-Kirschvink†, Charles Comiter, Shreya Gaddam, Taylor Joren, Emmanuele Grody, Johain Ounadjela, Ke Zhang, Baoliang Ge, Jeonwoong Kang, Ramnik Xavier, Peter So, Tommaso Biancalani†, Jian Shu†, Aviv Regev†, “Raman2RNA: Live-cell label-free prediction of single-cell RNA profiles by Raman microscopy,” Nature Biotechnology, 2024 (link). †corresponding authors
  • Charles Comiter, Eeshit Vaishnav, Metamia Ciampricotti, Bo Li, Yiming Yang, Scott J. Rodig, Madison Turner, Kathleen L. Pfaff, Judit Jane-Valbuena, Michal Slyper, Julia Waldman, Sebastian Vigneau, Jingyi Wu, Timothy R. Blosser, Asa Segerstolpe, Daniel Abravanel, Nikil Wagle, Xiaowei Zhuang, Charles M. Rudin, Johanna Klughammer, Orit Rozenblatt-Rosen, Koseki J. Kobayashi-Kirschvink, Jian Shu, Aviv Regev, “Accelerated multimodal tissue data analysis with SCHAF: the Single-Cell omics from Histology Analysis Framework,” Nature, under review
  • Koseki J. Kobayashi-Kirschvink, Hidenori Nakaoka, Kenichiro Kamei, Yuichi Wakamoto: “Predicting transcriptomic profiles by Raman microscopy,” The Biophysical Society of Japan, vol. 77, No. 1 (2019).
  • Koseki J. Kobayashi-Kirschvink, Hidenori Nakaoka, Arisa Oda, Ken-ichiro F. Kamei, Kazuki Nosho, Hiroko Fukushima, Yu Kanesaki, Shunsuke Yajima, Haruhiko Masaki, Kunihiro Ohta, Yuichi Wakamoto: “Linear Regression Links Transcriptomic Data and Cellular Raman Spectra,” Cell Systems, Volume 7, Issue 1, Pages 104-117.e4, 2018, link.
  • Nosho, K., Fukushima, H., Asai, T., Nishio, M., Takamaru, R., Kobayashi-Kirschvink, K., Ogawa, T., Hidaka, Masaki, H.: “cAMP-CRP acts as a key regulator for the viable but non-culturable state in Escherichia coli,” Microbiology 164(3), 410–419, 2018.
  • Koseki J. Kobayashi-Kirschvink, Hiromasa Oku: “Design Principles of a High-speed Omni-scannable Gaze Controller,” IEEE Robotics and Automation Letters, Vol. 1, Issue 2, p. 836-843, 2016.
  • Koseki J. Kobayashi-Kirschvink, King-Fai Li, Run-Lie Shia, and Yuk L, Yung, “Fundamental Modes of Atmospheric CFC-11 From Empirical Mode Decomposition,” Advances in Adaptive Data Analysis, Vol. 4, No. 4, pp. 1250024-1 – 1250024-17, 2013.

     

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